8-<scp>l</scp>-Cystinyl Bis(1,8-diazaspiro[4.5]decane) as an Orally Bioavailable <scp>l</scp>-Cystine Crystallization Inhibitor for Cystinuria-Reference-Cited by-同舟云学术

8-l-Cystinyl Bis(1,8-diazaspiro[4.5]decane) as an Orally Bioavailable l-Cystine Crystallization Inhibitor for Cystinuria

Published:2024-06-06 Issue:7 Volume:15 Page:1026-1031
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Hu Longqin¹²^ORCID,Albanyan Haifa¹,Yang Jeffrey¹,Wang Yiling¹,Yang Min³,Tan Xiangduan¹,Zhong Xiaodi⁴,Ward Michael D.⁴^ORCID,Sahota Amrik³

Affiliation:

1. Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, United States

2. The Cancer Institute of New Jersey, New Brunswick, New Jersey 08901, United States

3. Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, United States

4. Molecular Design Institute, Department of Chemistry, New York University, New York, New York 10003, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.4c00066

Reference26 articles.

1. How should patients with cystine stone disease be evaluated and treated in the twenty-first century?

2. Hereditary causes of kidney stones and chronic kidney disease

3. Cystinuria: an inborn cause of urolithiasis

4. Cystinuria: current concepts and future directions

5. Cystinuria: genetic aspects, mouse models, and a new approach to therapy

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