Identification of 5-Thiocyanatothiazol-2-amines Disrupting WDR5-MYC Protein–Protein Interactions

Author:

Wang Haiyang1,Zhou Yihui12,Lu Li1,Cen Jie1,Wu Zhenying1,Yang Bo134,Zhu Chengliang1356,Cao Ji1347,Yu Yongping187ORCID,Chen Wenteng17ORCID

Affiliation:

1. Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

2. Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China

3. Engineering Research Center of Innovative Anticancer Drugs, Ministry of Education, Hangzhou 310000, China

4. Center for Medical Research and Innovation in Digestive System Tumors, Ministry of Education, Hangzhou 310020, China

5. Center for Drug Safety Evaluation and Research of ZJU, Hangzhou 310058, China

6. Cancer Center, Zhejiang University, Hangzhou City 310058, China

7. Jinhua Institute of Zhejiang University, Jinhua 321299, China

8. School of Pharmacy, Xinjiang Medical University, Urumqi 830054, China

Funder

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

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