INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology-Reference-Cited by-同舟云学术

INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology

Published:2017-03-06 Issue:5 Volume:8 Page:486-491
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Yue Eddy W.¹,Sparks Richard¹,Polam Padmaja¹,Modi Dilip¹,Douty Brent¹,Wayland Brian¹,Glass Brian¹,Takvorian Amy¹,Glenn Joseph¹,Zhu Wenyu¹,Bower Michael¹,Liu Xiangdong¹,Leffet Lynn¹,Wang Qian¹,Bowman Kevin J.¹,Hansbury Michael J.¹,Wei Min¹,Li Yanlong¹,Wynn Richard¹,Burn Timothy C.¹,Koblish Holly K.¹,Fridman Jordan S.¹,Emm Tom¹,Scherle Peggy A.¹,Metcalf Brian¹,Combs Andrew P.¹^ORCID

Affiliation:

1. Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.6b00391

Reference37 articles.

1. Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

2. Pembrolizumab versus Ipilimumab in Advanced Melanoma

3. Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma