Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus

Author:

Fader Lee1,Brault Martine1,Desjardins Jessica1,Dansereau Nathalie1,Lamorte Louie1,Tremblay Sonia1,Bilodeau François1,Bordeleau Josée1,Duplessis Martin1,Gorys Vida1,Gillard James1,Gleason James L.1,James Clint1,Joly Marc-André1,Kuhn Cyrille1,Llinas-Brunet Montse1,Luo Laibin1,Morency Louis1,Morin Sébastien1,Parisien Mathieu1,Poirier Maude1,Thibeault Carl1,Trinh Thao1,Sturino Claudio1,Srivastava Sanjay1,Yoakim Christiane1,Franti Michael1

Affiliation:

1. Research and Development, Boehringer Ingelheim (Canada) Ltd., 2100 Cunard Street, Laval, Québec H7S 2G5, Canada

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference13 articles.

1. The pathogenesis of human cytomegalovirus

2. An update on the management and prevention of cytomegalovirus infection following allogeneic hematopoietic stem cell transplantation

3. Progress on pursuit of human cytomegalovirus vaccines for prevention of congenital infection and disease

4. Development of a high-throughput human cytomegalovirus quantitative PCR cell-based assay

5. Fader, L.; Parisien, M.; Thibeault, C.; Morency, L.; Duplessis, M.; James, C.; Morin, S.; Gillard, J.Preparation of phenylacetylaminophenylthiazolecarboxamide derivatives and analogs for use as cytomegalovirus inhibitors. PCT Int. Appl., WO 2014/70979.

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