Structural Basis for the Effective Myostatin Inhibition of the Mouse Myostatin Prodomain-Derived Minimum Peptide-Reference-Cited by-同舟云学术

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Structural Basis for the Effective Myostatin Inhibition of the Mouse Myostatin Prodomain-Derived Minimum Peptide

Published:2016-11-29 Issue:1 Volume:8 Page:113-117
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Asari Tomo¹,Takayama Kentaro¹,Nakamura Akari¹,Shimada Takahiro¹,Taguchi Akihiro¹,Hayashi Yoshio¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

Funder

Ministry of Education, Culture, Sports, Science, and Technology

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.6b00420

Reference17 articles.

1. Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member

2. Induction of Cachexia in Mice by Systemically Administered Myostatin

3. Functional improvement of dystrophic muscle by myostatin blockade

4. Characterization and identification of the inhibitory domain of GDF-8 propeptide

5. The Myostatin Propeptide and the Follistatin-related Gene Are Inhibitory Binding Proteins of Myostatin in Normal Serum

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1. Inhibitor Design Strategy for Myostatin: Dynamics and Interaction Networks Define the Affinity and Release Mechanisms of the Inhibited Complexes;Molecules;2023-07-26

2. Inactivation of myostatin by photooxygenation using functionalized d-peptides;RSC Medicinal Chemistry;2023

3. Peptide Tool-Driven Functional Elucidation of Biomolecules Related to Endocrine System and Metabolism;Chemical and Pharmaceutical Bulletin;2022-06-01

4. Development of Myostatin Inhibitory d-Peptides to Enhance the Potency, Increasing Skeletal Muscle Mass in Mice;ACS Medicinal Chemistry Letters;2022-02-14

5. The role of pro-domains in human growth factors and cytokines;Biochemical Society Transactions;2021-09-08

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