DNA-Encoded Library Hit Confirmation: Bridging the Gap Between On-DNA and Off-DNA Chemistry-Reference-Cited by-同舟云学术

DNA-Encoded Library Hit Confirmation: Bridging the Gap Between On-DNA and Off-DNA Chemistry

Published:2021-06-03 Issue:7 Volume:12 Page:1166-1172
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Xia Bing¹^ORCID,Franklin G. Joseph¹,Lu Xiaojie¹^ORCID,Bedard Katie L.¹,Grady LaShadric C.¹,Summerfield Jennifer D.¹,Shi Eric X.¹,King Bryan W.²,Lind Kenneth E.¹,Chiu Cynthia¹,Watts Eleanor¹,Bodmer Vera¹,Bai Xiaopeng¹,Marcaurelle Lisa A.¹^ORCID

Affiliation:

1. Encoded Library Technologies/NCE Molecular Discovery, R&D Medicinal Science and Technology, GlaxoSmithKline, 200 Cambridge Park Drive, Cambridge, Massachusetts 02140, United States

2. Encoded Library Technologies/NCE Molecular Discovery, R&D Medicinal Science and Technology, GlaxoSmithKline, Collegeville, Pennsylvania 19426, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00156

Reference33 articles.

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2. Innovation in the pharmaceutical industry: New estimates of R&D costs

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5. Integration of Lead Discovery Tactics and the Evolution of the Lead Discovery Toolbox

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