N-Trifluoromethylthiolated Sulfonimidamides and Sulfoximines: Anti-microbial, Anti-mycobacterial, and Cytotoxic Activity

Author:

Thota Niranjan1,Makam Parameshwar1,Rajbongshi Kamal K.1,Nagiah Savania2,Abdul Naeem Sheik2,Chuturgoon Anil A2ORCID,Kaushik Amit3,Lamichhane Gyanu3,Somboro Anou M.4,Kruger Hendrik G.1ORCID,Govender Thavendran5,Naicker Tricia1,Arvidsson Per I16ORCID

Affiliation:

1. Catalysis and Peptide Research Unit, University of KwaZulu Natal, Durban 4001, South Africa

2. Discipline of Medical Biochemistry, University of KwaZulu-Natal, Durban 4001, South Africa

3. Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, United States

4. Biomedical Resource Unit, College of Health Science, University of KwaZulu-Natal, Durban 4001, South Africa

5. Ansynth Pty Ltd., 498 Grove End Drive, Phoenix, Durban 4068, South Africa

6. Science for Life Laboratory Drug Discovery and Development Platform and Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 171 77, Sweden

Funder

National Research Foundation

School of Health Sciences, University of KwaZulu-Natal

Medicinal Research Council

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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