Trends in Hit-to-Lead Optimization Following DNA-Encoded Library Screens-Reference-Cited by-同舟云学术

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Trends in Hit-to-Lead Optimization Following DNA-Encoded Library Screens

Published:2021-02-11 Issue:3 Volume:12 Page:343-350
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Reiher Christopher A.¹^ORCID,Schuman David P.²,Simmons Nicholas²^ORCID,Wolkenberg Scott E.¹^ORCID

Affiliation:

1. Discovery Chemistry, Janssen Research & Development, LLC, Welsh & McKean Roads, Spring House, Pennsylvania 19477, United States

2. Discovery Chemistry, Janssen Research & Development, LLC, 3210 Merryfield Row, San Diego, California 92121, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.0c00615

Reference35 articles.

1. Impact of high-throughput screening in biomedical research

2. DNA-Encoded Library Technology: A Brief Guide to Its Evolution and Impact on Drug Discovery

3. Integration of Lead Discovery Tactics and the Evolution of the Lead Discovery Toolbox

4. Where Do Recent Small Molecule Clinical Development Candidates Come From?

5. DNA-Encoded Libraries in the Pharmaceutical Industry

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