Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol-Reference-Cited by-同舟云学术

Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol

Published:2023-04-20 Issue:5 Volume:14 Page:614-620
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Beers Jessica L.¹^ORCID,Authement Aurora K.²^ORCID,Isoherranen Nina²^ORCID,Jackson Klarissa D.¹^ORCID

Affiliation:

1. Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, North Carolina 27599, United States

2. Department of Pharmaceutics, University of Washington School of Pharmacy, Seattle, Washington 98195, United States

Funder

University of Washington

National Institute on Drug Abuse

National Institute of General Medical Sciences

Eshelman School of Pharmacy, University of North Carolina at Chapel Hill

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00017

Reference37 articles.

1. The pharmacokinetics and the pharmacodynamics of cannabinoids

2. The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin

3. Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor

4. Greenwich Biosciences. EPIDIOLEX® (cannabidiol) prescribing information, 2023. https://www.epidiolex.com/sites/default/files/pdfs/1120/EPX-03645-1120_EPIDIOLEX_(cannabidiol)_USPI.pdf.

5. The proposed mechanisms of action of CBD in epilepsy

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metabolism and liver toxicity of cannabidiol;Journal of Environmental Science and Health, Part C;2024-06-21

2. Development and Scale-Up of 7-COOH CBD Synthesis, a Key Cannabinoid Metabolite;Organic Process Research & Development;2024-05-15

3. CBD and THC in Special Populations: Pharmacokinetics and Drug–Drug Interactions;Pharmaceutics;2024-04-01

4. CYP2C9, CYP3A and CYP2C19 metabolize Δ9-tetrahydrocannabinol to multiple metabolites but metabolism is affected by human liver fatty acid binding protein (FABP1);Biochemical Pharmacology;2024-04

5. The impact of pregnancy and associated hormones on the pharmacokinetics of Δ ⁹ -tetrahydrocannabinol;Expert Opinion on Drug Metabolism & Toxicology;2024-02