Selective Irreversible Inhibitors of the Wnt-Deacylating Enzyme NOTUM Developed by Activity-Based Protein Profiling-Reference-Cited by-同舟云学术

Selective Irreversible Inhibitors of the Wnt-Deacylating Enzyme NOTUM Developed by Activity-Based Protein Profiling

Published:2018-05-26 Issue:6 Volume:9 Page:563-568
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Suciu Radu M.¹,Cognetta Armand B.¹,Potter Zachary E.¹,Cravatt Benjamin F.¹^ORCID

Affiliation:

1. The Skaggs Institute for Chemical Biology, Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California 92037, United States

Funder

National Cancer Institute

National Institute on Drug Abuse

Skaggs Institute for Chemical Biology

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00191

Reference31 articles.

1. Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors

2. THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE

3. Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture

4. Function and biological roles of the Dickkopf family of Wnt modulators

5. Wnt acylation and its functional implication in Wnt signalling regulation

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