Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library-Reference-Cited by-同舟云学术

Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library

Published:2017-09-28 Issue:10 Volume:8 Page:1122-1127
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Testero Sebastián A.¹,Granados Carla²,Fernández Daniel²,Gallego Pablo²,Covaleda Giovanni²,Reverter David²,Vendrell Josep²,Avilés Francesc X.²,Pallarès Irantzu²,Mobashery Shahriar¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States

2. Departament de Bioquímica i Biologia Molecular, Facultat de Biociències, and Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Spain

Funder

Ministerio de Econom?a y Competitividad

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.7b00346

Reference33 articles.

1. The Degradome database: expanding roles of mammalian proteases in life and disease

2. C-terminomics Screen for Natural Substrates of Cytosolic Carboxypeptidase 1 Reveals Processing of Acidic Protein C termini

3. Carboxypeptidases in disease: Insights from peptidomic studies