Synthesis and Uptake of Fluorescence-Labeled Combi-molecules by P-Glycoprotein-Proficient and -Deficient Uterine Sarcoma Cells MES-SA and MES-SA/DX5-Reference-Cited by-同舟云学术

Synthesis and Uptake of Fluorescence-Labeled Combi-molecules by P-Glycoprotein-Proficient and -Deficient Uterine Sarcoma Cells MES-SA and MES-SA/DX5

Published:2010-02-12 Issue:5 Volume:53 Page:2104-2113
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Larroque-Lombard Anne-Laure¹,Todorova Margarita¹,Golabi Nahid¹,Williams Christopher²,Jean-Claude Bertrand J.¹

Affiliation:

1. Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, McGill University Health Center/Royal Victoria Hospital, 687 Pine Avenue West Room M-719, Montreal, Quebec, H3A 1A1 Canada

2. Chemical Computing Group Inc., 1010 Sherbrooke Street West, Suite 910, Montreal, Quebec H3A 2R7, Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9016043

Reference27 articles.

1. Human P-Glycoprotein Exhibits Reduced Affinity for Substrates during a Catalytic Transition State

2. The P-Glycoprotein Efflux Pump: How Does it Transport Drugs?

3. Targeting multidrug resistance in cancer

4. Molecular mechanisms of drug resistance

5. Recent Progress in Understanding the Mechanism of P-Glycoprotein-mediated Drug Efflux

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