Spiro[(dihydropyrazin-2,5-dione)-6,3′-(2′,3′-dihydrothieno[2,3-b]naphtho-4′,9′-dione)]-Based Cytotoxic Agents: Structure–Activity Relationship Studies on the Substituent at N4-Position of the Diketopiperazine Domain-Reference-Cited by-同舟云学术

Spiro[(dihydropyrazin-2,5-dione)-6,3′-(2′,3′-dihydrothieno[2,3-b]naphtho-4′,9′-dione)]-Based Cytotoxic Agents: Structure–Activity Relationship Studies on the Substituent at N4-Position of the Diketopiperazine Domain

Published:2008-04-23 Issue:10 Volume:51 Page:2924-2932
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gomez-Monterrey Isabel¹,Campiglia Pietro¹,Carotenuto Alfonso¹,Stiuso Paola¹,Bertamino Alessia¹,Sala Marina¹,Aquino Claudio¹,Grieco Paolo¹,Morello Silvana¹,Pinto Aldo¹,Ianelli Pio¹,Novellino Ettore¹

Affiliation:

1. Dipartimento di Chimica Farmaceutica e Tossicologica, University of Naples “Federico II”, 80131 Napoli, Dipartimento di Scienze Farmaceutica, Università di Salerno, I-84084, Fisciano, Salerno, and Dipartimento di Biochimica e Biofisica “Francesco Cetrangolo”, Seconda Università di Napoli, 80138 Napoli

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm7013056

Reference24 articles.

1. Anthracycline and anthraquinone anticancer agents: Current status and recent developments

2. Anthracyclines: Selected New Developments

3. 2 The Design, Synthesis and Development of a New Class of Potent Antineoplastic Anthraquinones

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