Improved Process for the Preparation of Montelukast: Development of an Efficient Synthesis, Identification of Critical Impurities and Degradants
Author:
Affiliation:
1. Zentiva k.s., Department of Chemical Synthesis, U kabelovny 130, Prague 102 01, Czech Republic
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op900311z
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2. Single dose pharmacokinetics, safety and tolerability of MK‐0476, a new leukotriene D4‐receptor antagonist, in healthy volunteers.
3. Montelukast
4. Montelukast, a potent leukotriene receptor antagonist, causes dose-related improvements in chronic asthma
5. Belley, M. L.; Leger, S.; Roy, P.; Xiang, Y. B.; Labelle, M.; Guay, D.EP 0480717 B1 (Merck Frost, 1992) .
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