Modular Development of Enzyme-Activatable Proteolysis Targeting Chimeras for Selective Protein Degradation and Cancer Targeting-Reference-Cited by-同舟云学术

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Modular Development of Enzyme-Activatable Proteolysis Targeting Chimeras for Selective Protein Degradation and Cancer Targeting

Published:2024-05-16 Issue:7 Volume:4 Page:2564-2577
ISSN:2691-3704
Container-title:JACS Au
language:en
Short-container-title:JACS Au

Author:

Chen Yanchi¹²,Zhang Lina¹,Fang Lincheng¹,Chen Chengjie¹,Zhang Dong¹,Peng Tao¹³^ORCID

Affiliation:

1. State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China

2. National Key Laboratory of Non-Food Biomass Energy Technology, National Engineering Research Center for Non-Food Biorefinery, Institute of Grand Health, Guangxi Academy of Sciences, 98 Daling Road, Nanning 530007, China

3. Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen 518132, China

Funder

Science, Technology and Innovation Commission of Shenzhen Municipality

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/jacsau.4c00298

Reference83 articles.

1. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

2. Induced protein degradation: an emerging drug discovery paradigm

3. PROteolysis TArgeting Chimeras (PROTACs) — Past, present and future

4. PROTAC targeted protein degraders: the past is prologue

5. PROTACs: past, present and future

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