Design, Synthesis, and Evaluation in Vitro of Quinoline-8-carboxamides, a New Class of Poly(adenosine-diphosphate-ribose)polymerase-1 (PARP-1) Inhibitor-Reference-Cited by-同舟云学术

Design, Synthesis, and Evaluation in Vitro of Quinoline-8-carboxamides, a New Class of Poly(adenosine-diphosphate-ribose)polymerase-1 (PARP-1) Inhibitor

Published:2008-12-31 Issue:3 Volume:52 Page:868-877
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lord Anna-Marie¹,Mahon Mary F.¹,Lloyd Matthew D.¹,Threadgill Michael D.¹

Affiliation:

1. Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, U.K., and X-ray Crystallography Unit, Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8013629

Reference61 articles.

1. Poly ADP-ribose polymerase-1: An international molecule of mystery

2. Poly(ADP-ribose)polymerase Inhibition - Where Now?

3. Poly(ADP-ribose): novel functions for an old molecule

4. Poly-ADP-ribosylation in health and disease

5. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

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