Optimized Synthesis and Enhanced Efficacy of Novel Triplex-Forming Camptothecin Derivatives Based on Gimatecan-Reference-Cited by-同舟云学术

Optimized Synthesis and Enhanced Efficacy of Novel Triplex-Forming Camptothecin Derivatives Based on Gimatecan

Published:2009-03-23 Issue:4 Volume:20 Page:666-672
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Vekhoff Pierre¹,Halby Ludovic¹,Oussedik Kahina¹,Dallavalle Sabrina¹,Merlini Lucio¹,Mahieu Christine¹,Lansiaux Amélie¹,Bailly Christian¹,Boutorine Alexandre¹,Pisano Claudio¹,Giannini Giuseppe¹,Alloatti Domenico¹,Arimondo Paola B.¹

Affiliation:

1. CNRS UMR5153, Muséum National d’Histoire Naturelle USM0503, and INSERM U565, 43 rue Cuvier, 75231 Paris cedex 05, France, UPMC, Paris 75005, France, DISMA, Università di Milano, via Celoria 2, 20133 Milano, Italy, INSERM U-837, COL, IRCL, Place Verdun, 59045 Lille, France, and Sigma-tau Industrie Farmaceutiche Riunite SpA, Pomezia, Italy

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc800494y

Reference20 articles.

1. Topoisomerase I inhibitors: camptothecins and beyond

2. Cellular roles of DNA topoisomerases: a molecular perspective

3. Camptothecin: current perspectives

4. Directing Topoisomerase I Mediated DNA Cleavage to Specific Sites by Camptothecin Tethered to Minor- and Major-Groove Ligands

5. Design and Optimization of Camptothecin Conjugates of Triple Helix-forming Oligonucleotides for Sequence-specific DNA Cleavage by Topoisomerase I

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