Efficient Synthesis of [2‘-18O]Uridine and Its Incorporation into Oligonucleotides: A New Tool for Mechanistic Study of Nucleotidyl Transfer Reactions by Isotope Effect Analysis-Reference-Cited by-同舟云学术

Efficient Synthesis of [2‘-18O]Uridine and Its Incorporation into Oligonucleotides: A New Tool for Mechanistic Study of Nucleotidyl Transfer Reactions by Isotope Effect Analysis

Published:2007-12-04 Issue:1 Volume:73 Page:309-311
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Dai Qing¹,Frederiksen John K.¹,Anderson Vernon E.¹,Harris Michael E.¹,Piccirilli Joseph A.¹

Affiliation:

1. Department of Biochemistry & Molecular Biology, Department of Chemistry, and Howard Hughes Medical Institute, The University of Chicago, 929 East 57th Street, MC 1028, Chicago, Illinois 60637, and Department of Biochemistry and Center for RNA Molecular Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106 jpicciri@uchicago.edu; meh2@cwru.edu

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo701727h

Reference34 articles.

1. Kinetics and Mechanisms for the Cleavage and Isomerization of the Phosphodiester Bonds of RNA by Brønsted Acids and Bases

2. Uses of Isotope Effects in the Study of Enzymes

3. Isotope effects in the study of enzymatic phosphoryl transfer reactions

4. Activation of Oxygen Nucleophiles in Enzyme Catalysis

5. Synthesis of ribose and of adenine nucleotides containing oxygen-18

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