Antitumor Agents. 194. Synthesis and Biological Evaluations of 4-β-Mono-, -Di-, and -Trisubstituted Aniline-4‘-O-demethyl-podophyllotoxin and Related Compounds with Improved Pharmacological Profiles-Reference-Cited by-同舟云学术

Antitumor Agents. 194. Synthesis and Biological Evaluations of 4-β-Mono-, -Di-, and -Trisubstituted Aniline-4‘-O-demethyl-podophyllotoxin and Related Compounds with Improved Pharmacological Profiles

Published:1999-06-16 Issue:13 Volume:42 Page:2441-2446
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhu Xiao-Kang¹,Guan Jian¹,Tachibana Yoko¹,Bastow Kenneth F.¹,Cho Sung Jin¹,Cheng Huey-Hwa¹,Cheng Yung-Chi¹,Gurwith Marc¹,Lee Kuo-Hsiung¹

Affiliation:

1. Division of Medicinal Chemistry and Natural Products, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06510, and Genelabs Technologies, Inc., Redwood City, California 94063

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990055f

Reference18 articles.

1. Jardine, I. Podophyllotoxins. InAnticancer Agents Based on NaturalProducts Modesl; Cassady, J. M., Douros, J., Eds.; Academic Press: New York, 1980; pp 319−351 and references therein.

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