Defining Molecular Initiating Events in the Adverse Outcome Pathway Framework for Risk Assessment-Reference-Cited by-同舟云学术

Defining Molecular Initiating Events in the Adverse Outcome Pathway Framework for Risk Assessment

Published:2014-11-10 Issue:12 Volume:27 Page:2100-2112
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Allen Timothy E. H.¹,Goodman Jonathan M.¹,Gutsell Steve²,Russell Paul J.²

Affiliation:

1. Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom

2. Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, United Kingdom

Funder

Unilever

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx500345j

Reference166 articles.

1. OECD (2012) ,Proposal for a Template, and Guidance on Developing and Assessing the Completeness of Adverse Outcome Pathways, Appendix I, Collection of Working Definitions,http:/www.oecd.org/chemicalsafety/testingofchemicals/49963576.pdf.

2. Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

3. European Molecular Biology Laboratory–European Bioinformatics Institute, ChEMBL database, https://www.ebi.ac.uk/chembl/.

4. Compound bioactivities go public

5. PubChem: a public information system for analyzing bioactivities of small molecules

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