1. Contribution from the Department of Chemistry and Biochemistry, University of California at San Diego, 9500 Gilman Drive, La Jolla, California 92093-0365, Center for Theoretical Biological Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, California 92093-0374, Interdisciplinary Centre for Mathematical and Computational Modelling, Warsaw University, 02-106 Warsaw, Poland, Howard Hughes Medical Institute and Department of Pharmacology, University of California at San Diego, La...