1. Department of Surgery, The University of Michigan Medical Center, Ann Arbor, Michigan 48109, Department of Chemistry, The University of Michigan, Ann Arbor, Michigan 48109, Department of Internal Medicine, Division of Nephrology, The University of Michigan, Ann Arbor, Michigan 48109, Department of Surgery, The University of Florida, Jacksonville, Florida 32009, and Comprehensive Cancer Center, The University of Michigan Medical Center, Ann Arbor, Michigan 48109