New Series of Antiprion Compounds: Pyrazolone Derivatives Have the Potent Activity of Inhibiting Protease-Resistant Prion Protein Accumulation-Reference-Cited by-同舟云学术

New Series of Antiprion Compounds: Pyrazolone Derivatives Have the Potent Activity of Inhibiting Protease-Resistant Prion Protein Accumulation

Published:2007-09-13 Issue:21 Volume:50 Page:5053-5056
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kimata Ayako¹,Nakagawa Hidehiko¹,Ohyama Ryo¹,Fukuuchi Tomoko¹,Ohta Shigeru¹,Suzuki Takayoshi¹,Miyata Naoki¹

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1, Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan, and Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Koshingai, Hiro, Kure, Hiroshima 737-0112, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070688r

Reference26 articles.

1. Molecular Biology of Prion Diseases

2. A crucial role for B cells in neuroinvasive scrapie

3. Normal prion protein has an activity like that of superoxide dismutase

4. Copper Stimulates Endocytosis of the Prion Protein

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