Thermodynamics of Binding of Structurally Similar Ligands to Histone Deacetylase 8 Sheds Light on Challenges in the Rational Design of Potent and Isozyme-Selective Inhibitors of the Enzyme-Reference-Cited by-同舟云学术

Thermodynamics of Binding of Structurally Similar Ligands to Histone Deacetylase 8 Sheds Light on Challenges in the Rational Design of Potent and Isozyme-Selective Inhibitors of the Enzyme

Published:2014-11-26 Issue:48 Volume:53 Page:7445-7458
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Singh Raushan K.¹,Suzuki Takayoshi²,Mandal Tanmay¹,Balsubramanian Narayanaganesh¹,Haldar Manas³,Mueller Dustin J.¹,Strode Jerrod A.¹,Cook Gregory¹,Mallik Sanku³,Srivastava D. K.¹

Affiliation:

1. Department of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58102, United States

2. Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 603-8334, Japan

3. Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States

Funder

National Center for Research Resources

National Cancer Institute

Division of Materials Research

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi500711x

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