2-(3-Aryl-3-oxopropen-1-yl)-9-tert-butyl-paullones: A New Antileishmanial Chemotype-Reference-Cited by-同舟云学术

2-(3-Aryl-3-oxopropen-1-yl)-9-tert-butyl-paullones: A New Antileishmanial Chemotype

Published:2008-01-11 Issue:3 Volume:51 Page:659-665
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Reichwald Christina¹,Shimony Orly¹,Dunkel Ute¹,Sacerdoti-Sierra Nina¹,Jaffe Charles L.¹,Kunick Conrad¹

Affiliation:

1. Technische Universität Braunschweig, Institut für Pharmazeutische Chemie, Beethovenstraße 55, 38106 Braunschweig, Germany, and Department of Parasitology, Hebrew University—Hadassah Medical School, Post Office Box 12272, Jerusalem 91120, Israel

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm7012166

Reference37 articles.

1. Chemotherapy of Leishmaniasis: Past, Present and Future

2. Synthese von 7,12-Dihydro-indolo[3,2-d][1]benzazepin-6-(5H)-onen und 6,11-Dihydro-thieno-[3′,2′:2,3]azepino[4,5-b]indol-5(4H)-on

3. Evaluation and Comparison of 3D-QSAR CoMSIA Models for CDK1, CDK5, and GSK-3 Inhibition by Paullones

4. Structure-Aided Optimization of Kinase Inhibitors Derived from Alsterpaullone

Cited by 66 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Hybrids of imidazole with indoline derivatives: Microwave assisted synthesis, molecular docking studies, possible biological activities;Journal of the Indian Chemical Society;2024-04

2. The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones;PLOS ONE;2023-11-30

3. An Effective Synthesis of Previously Unknown 7-Aryl Substituted Paullones;Molecules;2023-03-02

4. Target-Based Rational Improvement Strategies and Pitfalls in Leishmania Drug Discovery;Natural Product Based Drug Discovery Against Human Parasites;2023

5. Synthesis of indolo/pyrroloazepinone-oxindoles as potential cytotoxic, DNA-intercalating and Topo I inhibitors;Bioorganic Chemistry;2022-05