Phenylimidazolidin-2-one Derivatives as Selective 5-HT3 Receptor Antagonists and Refinement of the Pharmacophore Model for 5-HT3 Receptor Binding-Reference-Cited by-同舟云学术

Phenylimidazolidin-2-one Derivatives as Selective 5-HT3 Receptor Antagonists and Refinement of the Pharmacophore Model for 5-HT3 Receptor Binding

Published:1997-10-01 Issue:21 Volume:40 Page:3369-3380
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Heidempergher Franco¹,Pillan Antonio¹,Pinciroli Vittorio¹,Vaghi Fabrizio¹,Arrigoni Claudio¹,Bolis Giorgio¹,Caccia Carla¹,Dho Luciano¹,McArthur Robert¹,Varasi Mario¹

Affiliation:

1. CNS Research, Structure Based Drug Design-CAMD Unit, R&D-Analytical Chemistry, and Toxicology, Pharmacia & Upjohn, Viale Louis Pasteur, 10, 20014 Nerviano (Milano), Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970060o

Reference44 articles.

1. Molecular biology of 5-HT receptors

2. 5-HT3 receptors are membrane ion channels

3. Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel

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