UnyLinker: An Efficient and Scaleable Synthesis of Oligonucleotides Utilizing a Universal Linker Molecule: A Novel Approach To Enhance the Purity of Drugs-Reference-Cited by-同舟云学术

UnyLinker: An Efficient and Scaleable Synthesis of Oligonucleotides Utilizing a Universal Linker Molecule: A Novel Approach To Enhance the Purity of Drugs

Published:2008-05-01 Issue:3 Volume:12 Page:399-410
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Ravikumar Vasulinga T.¹,Kumar R. Krishna¹,Olsen Phil¹,Moore Max N.¹,Carty Recaldo L.¹,Andrade Mark¹,Gorman Dennis¹,Zhu Xuefeng¹,Cedillo Isaiah¹,Wang Zhiwei¹,Mendez Lucio¹,Scozzari Anthony N.¹,Aguirre Gerardo¹,Somanathan Ratnasamy¹,Berneès Sylvain¹

Affiliation:

1. Isis Pharmaceuticals, Inc. 2282 Faraday Avenue, Carlsbad, California 92008 U.S.A., Centro de Graduados e Investigación del Instituto Tecnológico de Tijuana, Apdo. Postal 1166, Tijuana, B.C., México, and DEP, Facultad de Ciencias Quı́micas, UANL, Guerrero y Progreso S/N, Col. Treviño, 64570, Monterrey, N.L., México

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op8000178

Reference99 articles.

1. Vitravene and Macugen are two oligonucleotide-based drugs approved by the FDA.

2. Antisense Strategies

3. Progress in Antisense Technology

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