Structural and Stereoelectronic Requirements for the Inhibition of Mammalian 2,3-Oxidosqualene Cyclase by Substituted Isoquinoline Derivatives-Reference-Cited by-同舟云学术

Structural and Stereoelectronic Requirements for the Inhibition of Mammalian 2,3-Oxidosqualene Cyclase by Substituted Isoquinoline Derivatives

Published:1996-01-01 Issue:12 Volume:39 Page:2302-2312
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Barth Martine M.¹,Binet Jean L.¹,Thomas Didier M.¹,de Fornel Daniel C.¹,Samreth Soth¹,Schuber Francis J.¹,Renaut Patrice P.¹

Affiliation:

1. Laboratoires Fournier SCA, 50 rue de Dijon, 21121 Daix, France, and Laboratoire de Chimie Bioorganique, URA CNRS 1386, Faculté de Pharmacie, 67400 Illkirch, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9504621

Reference67 articles.

1. Lovastatin and Simvastatin - Inhibitors of HMG CoA Reductase and Cholesterol Biosynthesis

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3. Regulation of the mevalonate pathway

4. Effects of 3.beta.-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell cultures

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