In Vitro to in Vivo Extrapolation and Physiologically Based Modeling of Cytochrome P450 Mediated Metabolism in Beagle Dog Gut Wall and Liver-Reference-Cited by-同舟云学术

In Vitro to in Vivo Extrapolation and Physiologically Based Modeling of Cytochrome P450 Mediated Metabolism in Beagle Dog Gut Wall and Liver

Author:

Heikkinen Aki T.¹²,Fowler Stephen²,Gray Lynn³,Li Jia⁴,Peng Ying⁴,Yadava Preeti⁴,Railkar Aruna⁴,Parrott Neil²

Affiliation:

1. Faculty of Health Sciences, School of Pharmacy, University of Eastern Finland, Kuopio, Finland

2. pRED, Pharma Research & Early Development, Non-Clinical Safety, F. Hoffmann-La Roche AG, Basel, Switzerland

3. pRED, Pharma Research & Early Development, Non-Clinical Safety, F. Hoffmann-La Roche Ltd., Nutley, New Jersey, United States

4. pRED, Pharma Research & Early Development, Pharmaceutical and Analytical R&D, F. Hoffmann-La Roche Ltd., Nutley, New Jersey, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

Reference67 articles.

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