Discovery of a Potent Antiosteoporotic Drug Molecular Scaffold Derived from Angelica sinensis and Its Bioinspired Total Synthesis

Author:

Zou Jian1,Qiu Zuo-Cheng123,Yu Qiang-Qiang1,Wu Jia-Ming1,Wang Yong-Heng1,Shi Ke-Da2,Li Yi-Fang1,He Rong-Rong1ORCID,Qin Ling2,Yao Xin-Sheng1ORCID,Wang Xin-Luan2,Gao Hao1ORCID

Affiliation:

1. Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education of China/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, People’s Republic of China

2. Translational Medicine R&D Center, Institute of Biomedical and Health Engineering/Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518057, People’s Republic of China

3. College of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, People’s Republic of China

Funder

National Key Research and Development Program of China

Basic and Applied Basic Research Foundation of Guangdong Province

National Natural Science Foundation of China

Guangdong-HongKong-Macao Universities Joint Laboratory for the Internationalization of Traditional Chinese Medicine

Young Elite Scientists Sponsorship Program by China Association of Chinese Medicine

Guangzhou Key Laboratory of Traditional Chinese Medicine and Disease Susceptibility

Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program

Guangzhou Basic and Applied Basic Research Foundation

Guangdong International Science and Technology Cooperation Base

Innovative and Research Teams Project of Guangdong Higher Education Institution

Guangdong Major Project of Basic and Applied Basic Research

Publisher

American Chemical Society (ACS)

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