A Fast-Binding, Functionally Reversible, COX-2 Radiotracer for CNS PET Imaging

Author:

Placzek Michael S.1,Wilton Daniel K.2,Weïwer Michel3ORCID,Manter Mariah A.145ORCID,Reid Sarah E.1,Meyer Christopher J.3,Campbell Arthur J.3,Bajrami Besnik3,Bigot Antoine3,Bricault Sarah1,Fayet Agathe3,Frouin Arnaud2,Gergits Frederick2,Gupta Mehak3,Jiang Wei3,Melanson Michelle3,Romano Chiara D.3,Riley Misha M.1,Wang Jessica M.1,Wey Hsiao-Ying1ORCID,Wagner Florence F.3,Stevens Beth267,Hooker Jacob M.145ORCID

Affiliation:

1. Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, United States

2. Department of Neurology and F.M. Kirby Neurobiology Center, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States

3. Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, Massachusetts 02142, United States

4. Lurie Center for Autism, 1 Maguire Road, Lexington, Massachusetts 02421, United States

5. Massachusetts General Hospital, 55 Fruit St., Boston, Massachusetts 02114, United States

6. Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, Massachusetts 02142, United

7. Howard Hughes Medical Institute, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States

Funder

National Institute of Neurological Disorders and Stroke

Huntington's Disease Society of America

Publisher

American Chemical Society (ACS)

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