Preparation of Pyrrolidine-Based PDE4 Inhibitors via Enantioselective Conjugate Addition of α-Substituted Malonates to Aromatic Nitroalkenes
Author:
Affiliation:
1. Department of Process Chemistry Research, Array BioPharma, 3200 Walnut Street, Boulder, Colorado 80301
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol060398p
Reference17 articles.
1. Recent Advances in PDE4 Inhibitors as Immunoregulators and Anti- Inflammatory Drugs
2. Short-term regulation of PDE4 activity
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