6-Substituted 2-Oxo-2H-1-benzopyran-3-carboxylic Acid as a Core Structure for Specific Inhibitors of Human Leukocyte Elastase-Reference-Cited by-同舟云学术

6-Substituted 2-Oxo-2H-1-benzopyran-3-carboxylic Acid as a Core Structure for Specific Inhibitors of Human Leukocyte Elastase

Published:1999-09-10 Issue:20 Volume:42 Page:4161-4171
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Doucet Caroline¹,Pochet Lionel¹,Thierry Nicole¹,Pirotte Bernard¹,Delarge Jacques¹,Reboud-Ravaux Michèle¹

Affiliation:

1. Laboratoire d'Enzymologie Moléculaire et Fonctionnelle, Département de Biologie Supramoléculaire et Cellulaire, Institut Jacques Monod, Universités Paris VI and Paris VII, Tour 43, 2, place Jussieu, F-75251 Paris Cedex 05, France, Laboratoire de Chimie Pharmaceutique, Université de Liège, 3, rue Fusch, B-4000 Liège, Belgium, and Département de Pharmacie, Facultés Universitaires Notre-Dame de la Paix, 61, rue de Bruxelles, B-5000 Namur, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990070k

Reference41 articles.

1. Synthetic Inhibitors of Elastase

2. Inhibition of serine proteases by peptidyl fluoromethyl ketones

3. The synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinases

4. The synthesis of lysylfluoromethanes and their properties as inhibitors of trypsin, plasmin and cathepsin B

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