Synthesis of Structural ADP-Ribose Analogues as Inhibitors for SARS-CoV-2 Macrodomain 1-Reference-Cited by-同舟云学术

Synthesis of Structural ADP-Ribose Analogues as Inhibitors for SARS-CoV-2 Macrodomain 1

Published:2024-06-27 Issue:27 Volume:26 Page:5700-5704
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Rijpkema Koen J.¹,Schuller Marion²,van der Veer Miriam S.¹,Rieken Sjoerd¹,Chang Diego L. R.¹,Balić Pascal¹,Todorov Alex¹,Minnee Hugo¹,Wijngaarden Sven¹,Matos Isaac A.²³,Hoch Nicolas C.³,Codée Jeroen D. C.¹^ORCID,Ahel Ivan²,Filippov Dmitri V.¹^ORCID

Affiliation:

1. Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands

2. Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom

3. Departamento de Bioquímica, Instituto de Química, Universidade de Sao Paulo, Av. Prof. Lineu Prestes, 748, Cidade Universitária, Sao Paulo 055800-000, Brasil

Funder

Wellcome Trust

Biotechnology and Biological Sciences Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Ovarian Cancer Research Alliance

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.4c01792

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5. The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection