Synthesis of (−)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition–Rearrangement and Cross-electrophile Coupling
Author:
Affiliation:
1. Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom
Funder
Engineering and Physical Sciences Research Council
Higher Education Commission, Pakistan
Sultanate of Oman
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.orglett.7b01513
Reference45 articles.
1. The squalestatings, novel inhibitors of squalene synthase produced by a species of Phoma. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.
2. The isolation and structure elucidation of zaragozic acid C, a novel potent squalene synthase inhibitor.
3. Binding Modes of Zaragozic Acid A to Human Squalene Synthase and Staphylococcal Dehydrosqualene Synthase
4. Guan, Z.; Wen, R.; Lam, B. L.PCT Int. Appl. WO 2014138586 A1, 2014.
5. Squalestatin Is an Inhibitor of Carotenoid Biosynthesis in Plasmodium falciparum
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