Scalable Synthesis of (−)-Rasfonin Enabled by a Convergent Enantioselective α-Hydroxymethylation Strategy
Author:
Affiliation:
1. Department of Chemistry, University of Rochester, Rochester, New York 14627, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.8b02222
Reference19 articles.
1. Rasfonin, a New Apoptosis Inducer in ras-dependent Cells from Talaromyces sp.
2. Absolute stereochemistry of TT-1 (rasfonin), an α-pyrone-containing natural product from a fungus, Trichurus terrophilus
3. Rasfonin, a novel 2-pyrone derivative, induces ras-mutated Panc-1 pancreatic tumor cell death in nude mice
4. Akt inhibition attenuates rasfonin-induced autophagy and apoptosis through the glycolytic pathway in renal cancer cells
5. Fungal secondary metabolites rasfonin induces autophagy, apoptosis and necroptosis in renal cancer cell line
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