Biological and Biophysical Properties of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Are Affected by the Presence of Short Alkyl Groups on the Phenyl Ring-Reference-Cited by-同舟云学术

Biological and Biophysical Properties of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Are Affected by the Presence of Short Alkyl Groups on the Phenyl Ring

Published:2010-02-09 Issue:5 Volume:53 Page:1937-1950
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Oger Frédérik¹,Lecorgne Aurélien²,Sala Elisa³,Nardese Vanessa³,Demay Florence¹,Chevance Soizic²,Desravines Danielle C.⁴,Aleksandrova Nataliia⁴,Guével Rémy Le¹,Lorenzi Simone⁵,Beccari Andrea R.⁵,Barath Peter⁶,Hart Darren J.⁴,Bondon Arnaud⁷,Carettoni Daniele³,Simonneaux Gérard²,Salbert Gilles¹

Affiliation:

1. Equipe SPARTE, UMR CNRS 6026-Université Rennes 1, Campus Beaulieu, Bâtiment 13, 35042 Rennes, France, Cedex

2. Equipe ICMV, UMR CNRS 6226-Université Rennes 1, Campus Beaulieu, Bâtiment 10C, 35042 Rennes, France, Cedex

3. Axxam, San Raffaele Biomedical Science Park via Olgettina 58, 20132 Milan, Italy

4. Unit of Virus Host-Cell Interactions, UJF-EMBL-CNRS, UMI 3265, 6 rue Jules Horowitz, BP181, 38042 Grenoble, France, Cedex 9

5. Dompé SpA Via Campo di Pile, I-67100 L'Aquila, Italy

6. Cancer Research Institute, Slovak Academy of Sciences, Vlarska 7, SK-833 91 Bratislava, Slovak Republic

7. Equipe RMN-ILP, Université de Rennes 1, UMR6026 CNRS, Campus de Villejean, Bat 05, 35033 Rennes, France, Cedex

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901561u

Reference39 articles.

1. The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

2. Sirtuins in mammals: insights into their biological function

3. Epigenetics, disease, and therapeutic interventions

4. Histone Deacetylase Inhibitors: From Bench to Clinic

5. Anticancer activities of histone deacetylase inhibitors

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