Fjord-region Benzo[g]chrysene-11,12-dihydrodiol and Benzo[c]phenanthrene-3,4-dihydrodiol as Substrates for Rat Liver Dihydrodiol Dehydrogenase (AKR1C9): Structural Basis for Stereochemical Preference-Reference-Cited by-同舟云学术

Fjord-region Benzo[g]chrysene-11,12-dihydrodiol and Benzo[c]phenanthrene-3,4-dihydrodiol as Substrates for Rat Liver Dihydrodiol Dehydrogenase (AKR1C9): Structural Basis for Stereochemical Preference

Published:2008-02-06 Issue:3 Volume:21 Page:668-677
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Shultz Carol A.¹,Palackal Nisha T.¹,Mangal Dipti¹,Harvey Ronald G.¹,Blair Ian A.¹,Penning Trevor M.¹

Affiliation:

1. Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, Centers for Cancer Pharmacology and Excellence in Environmental Toxicology, Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, and The Ben May Institute for Cancer Research, 929 East 57th Street, W421 Chicago, Illinois 60637

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx7003695

Reference50 articles.

1. Bjorseth, A. (1985)Handbook of Polycyclic Aromatic Hydrocarbons, CRC Press, OH.

2. Grimmer, G. (1977) Analysis of automobile exhaust condensates.IARC Sci. Pub.16, 29–39.

3. Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes.

4. Dihydrodiol Dehydrogenases and Polycyclic Aromatic Hydrocarbon Activation: Generation of Reactive and Redox Active o-Quinones

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