Cyclopropyl and Isopropyl Derivatives of 11-cis and 9-cis Retinals at C-9 and C-13: Subtle Steric Differences with Major Effects on Ligand Efficacy in Rhodopsin-Reference-Cited by-同舟云学术

Cyclopropyl and Isopropyl Derivatives of 11-cis and 9-cis Retinals at C-9 and C-13: Subtle Steric Differences with Major Effects on Ligand Efficacy in Rhodopsin

Published:2011-02-10 Issue:3 Volume:74 Page:383-390
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

deGrip Willem J.¹²,Bovee-Geurts Petra H. M.¹,Wang Yajie²,Verhoeven Michiel A.²,Lugtenburg Johan²

Affiliation:

1. Department of Biochemistry, UMCN 286, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands

2. Department of BioOrganic Photochemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA, Leiden, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np100744v

Reference98 articles.

1. The Molecular Basis of Visual Excitation

2. Ernst, O. P.; Hofmann, K. P.; Palczewski, K.InPhotoreceptors and Light Signalling;Batschauert, A., Ed.Royal Society of Chemistry:Cambridge, U.K., 2003; Vol.3, pp77−123.

3. G Protein–Coupled Receptor Rhodopsin

4. Site of Attachment of Retinal in Rhodopsin

5. Resonance Raman studies of bathorhodopsin: Evidence for a protonated Schiff base linkage

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and In Vivo Efficacy in a Plasmodium berghei Mouse Malaria Infection Model;J MED CHEM;2022

2. Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and In Vivo Efficacy in a Plasmodium berghei Mouse Malaria Infection Model;Journal of Medicinal Chemistry;2022-12-12

3. Isorhodopsin: An Undervalued Visual Pigment Analog;Colorants;2022-06-23

4. Rhodopsins: An Excitingly Versatile Protein Species for Research, Development and Creative Engineering;Frontiers in Chemistry;2022-06-22

5. Coupled HOOP signature correlates with quantum yield of isorhodopsin and analog pigments;Biochimica et Biophysica Acta (BBA) - Bioenergetics;2017-02