Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain-Reference-Cited by-同舟云学术

Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain

Published:2021-12-28 Issue:1 Volume:12 Page:762-776
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Zhou Yucong¹²,Tao Wentao¹²,Qi Zhen¹²,Wei Jianhua¹²,Shi Ting¹²^ORCID,Kang Qianjin¹²^ORCID,Zheng Jianting¹²^ORCID,Zhao Yilei¹²^ORCID,Bai Linquan¹²^ORCID

Affiliation:

1. State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China

2. Joint International Research Laboratory of Metabolic and Developmental Sciences, Shanghai Jiao Tong University, Shanghai 200240, China

Funder

Natural Science Foundation of Shanghai

National Natural Science Foundation of China

National Key R & D Program of China

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.1c04991

Reference34 articles.

1. Actinomycete-Derived Polyketides as a Source of Antibiotics and Lead Structures for the Development of New Antimicrobial Drugs

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3. Enzyme clustering accelerates processing of intermediates through metabolic channeling

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5. Isolation and characterisation of amphotericin B analogues and truncated polyketide intermediates produced by genetic engineering of Streptomyces nodosus

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