Dual Photoredox/Nickel-Catalyzed Conversion of Aryl Halides to Aryl Aminooxetanes: Computational Evidence for a Substrate-Dependent Switch in Mechanism
Author:
Affiliation:
1. Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
2. WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People’s Republic of China
Funder
Genentech
Publisher
American Chemical Society (ACS)
Subject
Catalysis,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acscatal.9b03596
Reference44 articles.
1. Bioisosterism: A Rational Approach in Drug Design
2. Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
3. Oxetanes as Versatile Elements in Drug Discovery and Synthesis
4. Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group
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