Enzymatic C3-Methylation of Indoles Using Methyltransferase PsmD─Crystal Structure, Catalytic Mechanism, and Preparative Applications-Reference-Cited by-同舟云学术

Enzymatic C3-Methylation of Indoles Using Methyltransferase PsmD─Crystal Structure, Catalytic Mechanism, and Preparative Applications

Published:2022-11-03 Issue:22 Volume:12 Page:14130-14139
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Amariei Diana A.¹,Pozhydaieva Nadiia¹^ORCID,David Benoit²,Schneider Pascal¹,Classen Thomas³^ORCID,Gohlke Holger²⁴,Weiergräber Oliver H.⁵,Pietruszka Jörg¹³^ORCID

Affiliation:

1. Institute of Bioorganic Chemistry & Bioeconomy Science Center (BioSC), Heinrich Heine University Düsseldorf in Forschungszentrum Jülich, Jülich 52426, Germany

2. Institute of Bio- and Geosciences (IBG-4: Bioinformatics), Forschungszentrum Jülich, Jülich 52426, Germany

3. Institute of Bio- and Geosciences (IBG-1: Bioorganic Chemistry) & Bioeconomy Science Center (BioSC) Forschungszentrum Jülich, Jülich 52426, Germany

4. Institute for Pharmaceutical and Medicinal Chemistry & Bioeconomy Science Center (BioSC), Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany

5. Institute of Biological Information Processing (IBI-7: Structural Biochemistry) & Jülich Centre for Structural Biology (JuStruct), Forschungszentrum Jülich, Jülich 52425, Germany

Funder

European Regional Development Fund

Nordrhein-Westfalen

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.2c04240

Reference43 articles.

1. Architectures, mechanisms and molecular evolution of natural product methyltransferases

2. Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions

3. The Methylation Effect in Medicinal Chemistry

4. Methyl Effects on Protein–Ligand Binding

5. Installing the “magic methyl” – C–H methylation in synthesis

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