Active Site Loop Engineering Abolishes Water Capture in Hydroxylating Sesquiterpene Synthases
Author:
Affiliation:
1. School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff, CF10 3AT, United Kingdom
2. School of Biochemistry, University of Bristol, University Walk, Bristol, BS8 1TD, United Kingdom
Funder
Biotechnology and Biological Sciences Research Council
Publisher
American Chemical Society (ACS)
Subject
Catalysis,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acscatal.3c03920
Reference24 articles.
1. Structural and Chemical Biology of Terpenoid Cyclases
2. Bacterial Diterpene Biosynthesis
3. Sesquiterpene synthases: Passive catalysts or active players?
4. Terpene synthases and the regulation, diversity and biological roles of terpene metabolism
5. Structural Basis for Cyclic Terpene Biosynthesis by Tobacco 5-Epi-Aristolochene Synthase
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