Engineering a de Novo Transport Tunnel-Reference-Cited by-同舟云学术

Engineering a de Novo Transport Tunnel

Published:2016-10-10 Issue:11 Volume:6 Page:7597-7610
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Brezovsky Jan¹,Babkova Petra¹,Degtjarik Oksana²³,Fortova Andrea¹,Gora Artur¹,Iermak Iuliia²³,Rezacova Pavlina⁴⁵,Dvorak Pavel¹,Smatanova Ivana Kuta²³,Prokop Zbynek¹,Chaloupkova Radka¹,Damborsky Jiri¹

Affiliation:

1. Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment RECETOX, Faculty of Science, Masaryk University, Kamenice 5/A13, 625 00 Brno, Czech Republic

2. Faculty of Science, University of South Bohemia in Ceske Budejovice, Branisovska 1760, 37005 Ceske Budejovice, Czech Republic

3. Center for Nanobiology and Structural Biology ASCR, Zamek 136, 37333 Nove Hrady, Czech Republic

4. Institute of Organic Chemistry and Biochemistry ASCR, v.v.i. Flemingovo nam. 2, 166 10 Prague 6, Czech Republic

5. Institute of Molecular Genetics of the ASCR, v.v.i. Videnska 1083, 142 20 Prague 4, Czech Republic

Funder

Ministerstvo Školství, Mládeže a Telovýchovy

Narodowe Centrum Nauki

Grantová Agentura Ceské Republiky

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.6b02081

Reference89 articles.

1. Analysis of Catalytic Residues in Enzyme Active Sites

2. Prokop, Z.; Gora, A.; Brezovsky, J.; Chaloupkova, R.; Stepankova, V.; Damborsky, J.InProtein Engineering Handbook;Lutz, S.; Bornscheuer, U. T., Eds.Wiley-VCH:Weinheim, Germany, 2012; Vol.3, pp421–464.

3. Substrate tunnels in enzymes: Structure-function relationships and computational methodology

4. Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate

5. A Single Mutation in a Tunnel to the Active Site Changes the Mechanism and Kinetics of Product Release in Haloalkane Dehalogenase LinB

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