Engineered Imine Reductase for Larotrectinib Intermediate Manufacture

Author:

Chen Qi1,Li Bo-Bo1,Zhang Lilan2,Chen Xin-Ru1,Zhu Xin-Xin1,Chen Fei-Fei1ORCID,Shi Min2,Chen Chun-Chi2,Yang Yu2,Guo Rey-Ting2ORCID,Liu Weidong3ORCID,Xu Jian-He1ORCID,Zheng Gao-Wei1ORCID

Affiliation:

1. State Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, Shanghai 200237, People’s Republic of China

2. State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan 430062, People’s Republic of China

3. Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, People’s Republic of China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Hubei Province

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

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