Synthesis and Structure−Activity Relationships of New Benzodioxinic Lactones as Potential Anticancer Drugs

Author:

Romero Manel1,Renard Pierre1,Caignard Daniel-Henry1,Atassi Ghanen1,Solans Xavier1,Constans Pere1,Bailly Christian1,Pujol Maria Dolors1

Affiliation:

1. Laboratori de Química Farmacèutica (Unitat Associada al CSIC), Facultat de Farmàcia, Universitat de Barcelona, Av. Diagonal 643, 08028-Barcelona, Spain, Les Laboratoires Servier, 1 rue Carle Hebert, 92415-Courbevoie Cedex, France, Departament de Cristallografia, Mineralogia i Dipòsits Minerals, Facultat de Geologia, Universitat de Barcelona, C/ Martí i Franquès s/n, 08028-Barcelona, Spain, and INSERM U-524, IRCL, Place de Verdum, 59045 Lille, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference52 articles.

1. (a) Doyle, T.W. InCancer and Chemotherapy; Crooke, S. T., Prestayko, A. W., Eds.; Academic Press:  New York, 1980; Vol. 1, pp 295−305.

2. (b) Carter, S. K.; Bakowski, M. T.; Hellmann, K. InChemotherapy of Cancer, 3rd edition; John Wiley & Sons:  New York, 1987; pp 43−52.

3. The Current Status of Camptothecin Analogues as Antitumor Agents

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