Screening of Selective Inhibitors of 1α,25-Dihydroxyvitamin D3 24-Hydroxylase Using Recombinant Human Enzyme Expressed in Escherichia coli
Author:
Affiliation:
1. Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, Wisconsin 53706, United States
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi101488p
Reference68 articles.
1. Evolution of our understanding of vitamin D
2. The vitamin D deficiency pandemic and consequences for nonskeletal health: Mechanisms of action
3. Nonclassic Actions of Vitamin D
4. Enzymes involved in the activation and inactivation of vitamin D
5. The 25-Hydroxyvitamin D 24-Hydroxylase
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