Practical Total Synthesis of the Anti-Influenza Drug GS-4104
Author:
Affiliation:
1. Gilead Sciences Inc., Process Chemistry, 353 Lakeside Drive, Foster City, California 94404
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo980330q
Reference24 articles.
1. Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity
2. Structure-activity relationships of carbocyclic influenza neuraminidase inhibitors
3. C3-Thia and C3-carba isosteres of a carbocyclic influenza neuraminidase inhibitor, (3R,4R,5S)-4-acetamido-5-amino-3-propoxyl-1-cyclohexene-1-carboxylic acid
4. Synthesis and activity of C2-substituted analogs of influenza neuraminidase inhibitor GS 4071
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