A Stable Amorphous Statin: Solid-State NMR and Dielectric Studies on Dynamic Heterogeneity of Simvastatin-Reference-Cited by-同舟云学术

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A Stable Amorphous Statin: Solid-State NMR and Dielectric Studies on Dynamic Heterogeneity of Simvastatin

Published:2014-02-14 Issue:3 Volume:11 Page:727-737
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Nunes Teresa G.,Viciosa M. Teresa,Correia Natália T.¹²,Danède F.¹,Nunes Rita G.³,Diogo Hermínio P.

Affiliation:

1. Unité Matériaux et Transformation (UMET), UMR CNRS 8207, UFR de Physique, BAT P5, Université Lille 1, 59655 Villeneuve d’Ascq, France

2. REQUIMTE/CQFB, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal

3. Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp400455r

Reference39 articles.

1. Emerging trends in the stabilization of amorphous drugs

2. For example:Brittain, H. G.; Grant, D. J. W.Polymorphism in Pharmaceutical Solids;Marcel Dekker, Inc.:New York, 1999; pp279–330.

3. NMR studies of organic polymorphs & solvates

4. Simvastatin: structure solution of two new low-temperature phases from synchrotron powder diffraction and ss-NMR

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