1. Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, ¶Department of Chemistry and Loker Hydrocarbon Research Institute, USC College, §Department of Clinical Pharmacy and Pharmaceutical Economics & Policy, School of Pharmacy, #Department of Molecular Microbiology and Immunology, Keck School of Medicine, and ‡Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, 90089